Details about PhD Studentship In Pharmacy And Optometry
PhD Studentship In Pharmacy And Optometry is offered for PhD degree in the field of Novel drug therapy for mitochondrial optic neuropathy. You can apply to this scholarship here. The deadline for the sending your application is 13 Nov 2015. This scholarship is provided by Cardiff University and the value of this scholarship is Full Funding, Studentship covers tuition fees and provides a stipend of Â£14,057 p.a. . This scholarship is open for: Open to UK/EU applicants.
- Deadline: 13 Nov 2015
- Scholarship value: Full Funding, Studentship covers tuition fees and provides a stipend of Â£14,057 p.a.
Located within Cardiff University, this project is a collaboration between two world class research departments: School of Optometry & Vision Sciences and School of Pharmacy & Pharmaceutical Sciences. It is envisaged that equal amounts of time will be spent working in each school, spending time in a number of dynamic groups.
About the project: There is a pressing need to identify novel molecules with significantly greater electron transport chain potency for patients with mitochondrial dysfunction. Mitochondria are central players in the life and death of cells and especially of neurons. Within the brain, the retina ranks amongst the highest energy-consuming systems and the energy-dependence of neurons in the retina is particularly striking. Consequently, strategies to modulate mitochondrial function using small molecules with a view to restore energy production and/or reduce levels of oxidative stress are a promising approach for the treatment of mitochondrial diseases.
This multidisciplinary project involves the development of new chemical structures which will be targetted to mitochondria. Consequently, the work comprises drug design using molecular modelling, synthesis and purification of the identified leads and evalution in a range of bioassays including a model of autosomal dominant optic atrophy. Finally the work will focus on drug delivery aspects to ensure optimal targetting of mitochodria.
- Residency: Full awards (fees plus maintenance stipend) are open to UK Nationals and EU students without further restrictions.
- Academic criteria: Applicants for a studentship must have obtained, or be about to obtain, a 2.1 degree or higher in Chemistry, Biochemistry and Pharmacy. Applications are particularly welcome from applicants who can demonstrate a track record in one or more of the areas mentioned.