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The Vesalius Research Center (VRC) has focused since 15 years its research interests on unraveling the molecular basis of angiogenesis (i.e. the formation of blood vessels) and translating these genetic insights in therapeutic concepts â€“ and, if possible, novel treatments. Since recently, the VRC has broadened its scope of interest and is now genuinely interested in the neurovascular linke in health and disease.
Therefore, the VRC uses interdisciplinary functional genomic and genetic research strategies, from the bench to the bedside, and back again. Clinical cancer trials with antibodies against PlGF, a disease-specific angiogenic factor with high safety profile, have started in the mean time.
The VRC aspires to address medically relevant questions and study important biological processes via interdisciplinary basic research. By unraveling the genetic basis, we hope to deconvolute complex biological diseases into definable targets, that can be used for development of novel therapeutic concepts.
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